Pathway · 1 proteins
Division-associated membrane parts
FtsQ and related cell-cycle proteins support envelope-associated division functions.
How it works
- FtsQ/DivIB, MinE, FtsW/RodA/SpoVE-family and FtsX-like annotations point to different division-associated functions. Localization, membrane construction and spatial control are separate tasks.
- Compatible division proteins assemble near the developing septum, where membrane-associated components help coordinate envelope growth with the division scaffold. MinE-family annotation suggests spatial-control chemistry rather than a wall-building enzyme.
- Family-level names do not settle whether each listed protein acts in septation, elongation or a particular regulatory complex. This grouping is a functional overview, not an experimentally established assembly order.
Grouped by the atlas’s curated pathway map. The table order is not a proven reaction order.
Its proteins
| Protein | EC | Reaction (UniProt) | Metal or cluster | Amino acids | Certainty |
|---|---|---|---|---|---|
| Uncharacterized protein aq_522 | — | — | — | 216 | Step named |
Also part of this pathway
These proteins are described under another pathway, but also take part here.
| Protein | EC | Reaction (UniProt) | Metal or cluster | Amino acids | Certainty |
|---|---|---|---|---|---|
| Probable peptidoglycan glycosyltransferase FtsWHome: Envelope assembly and division | 2.4.99.28 | [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans,octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+) | — | 448 | Step named |
Origins
Which membrane parts must be present for division to work?
None of the books searched discusses these parts in an origins context.
Division needs membrane-anchored proteins that tie the ring inside the cell to the wall-building enzymes outside, so that new wall is built inward exactly where the membrane is pinched.
The wider question for this part of the cell: origins for dividing into two cells.
Sources
- Atlas pathway grouping from the VF5 reference-genome system map (Deckert et al. 1998; Braakman & Smith 2014)
Other pathways in this group: Peptidoglycan precursors · Wall synthesis and remodeling · Division scaffold · Envelope assembly and division · Peptidoglycan biosynthesis · Not yet placed in a pathway